KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
28.79
Human Site:
T581
Identified Species:
42.22
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
T581
P
D
N
Q
P
L
K
T
P
C
F
T
L
H
Y
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
T673
P
D
N
Q
P
L
K
T
P
C
F
T
L
H
Y
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
T833
P
D
N
Q
P
L
K
T
P
C
F
T
L
H
Y
Dog
Lupus familis
XP_547953
806
90703
T588
P
D
N
Q
P
L
K
T
P
C
F
T
L
H
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
L557
I
D
F
G
F
A
R
L
R
P
Q
S
P
A
E
Rat
Rattus norvegicus
Q63531
735
82865
E511
Q
K
F
F
S
E
R
E
A
S
F
V
L
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
T498
P
D
N
Q
P
L
K
T
P
C
F
T
L
H
Y
Chicken
Gallus gallus
Q5F3L1
789
89022
T571
P
D
N
Q
P
L
K
T
P
C
F
T
L
H
Y
Frog
Xenopus laevis
P10665
733
82620
T516
E
A
S
S
V
L
F
T
V
C
K
T
V
E
N
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
L528
I
T
K
T
V
D
Y
L
H
C
Q
G
V
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
L780
K
D
K
P
R
Y
T
L
D
Y
A
P
P
E
M
Honey Bee
Apis mellifera
XP_395099
910
102507
T600
R
G
C
E
P
L
H
T
P
C
F
T
L
P
Y
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
P547
Q
V
L
R
K
M
T
P
C
F
T
L
Q
Y
A
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
S541
P
L
K
T
P
C
F
S
L
H
F
A
A
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
M260
H
L
H
E
K
G
I
M
H
R
D
L
K
P
E
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
R466
H
K
L
D
V
I
Y
R
D
L
K
P
E
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
100
N.A.
6.6
13.3
N.A.
100
100
26.6
6.6
N.A.
6.6
60
0
20
P-Site Similarity:
100
100
100
100
N.A.
20
26.6
N.A.
100
100
40
20
N.A.
6.6
66.6
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
7
0
0
7
0
7
7
7
7
7
% A
% Cys:
0
0
7
0
0
7
0
0
7
57
0
0
0
0
0
% C
% Asp:
0
50
0
7
0
7
0
0
13
0
7
0
0
0
0
% D
% Glu:
7
0
0
13
0
7
0
7
0
0
0
0
7
13
19
% E
% Phe:
0
0
13
7
7
0
13
0
0
7
57
0
0
0
0
% F
% Gly:
0
7
0
7
0
7
0
0
0
0
0
7
0
0
0
% G
% His:
13
0
7
0
0
0
7
0
13
7
0
0
0
38
7
% H
% Ile:
13
0
0
0
0
7
7
0
0
0
0
0
0
0
7
% I
% Lys:
7
13
19
0
13
0
38
0
0
0
13
0
7
0
0
% K
% Leu:
0
13
13
0
0
50
0
19
7
7
0
13
50
0
0
% L
% Met:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
7
% M
% Asn:
0
0
38
0
0
0
0
0
0
0
0
0
0
7
7
% N
% Pro:
44
0
0
7
50
0
0
7
44
7
0
13
13
19
0
% P
% Gln:
13
0
0
38
0
0
0
0
0
0
13
0
7
0
0
% Q
% Arg:
7
0
0
7
7
0
13
7
7
7
0
0
0
0
0
% R
% Ser:
0
0
7
7
7
0
0
7
0
7
0
7
0
0
0
% S
% Thr:
0
7
0
13
0
0
13
50
0
0
7
50
0
0
7
% T
% Val:
0
7
0
0
19
0
0
0
7
0
0
7
13
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
13
0
0
7
0
0
0
13
44
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _